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The M1 phenotype is commonly referred to as neurotoxic (116, 117)

Disorders generally are either imbalances due to too much or too little of an endocrine hormone being produced, or they can be tumors in the endocrine system - tumors are typically non-cancerous but can influence hormone regulation

doi: 10.1007/BF00301626

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One of my board members texted me as soon as it happened and I was able to tune in and watch the live coverage for about 45 minutes, which was just very unsettling to watch