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These effects include the reduction of inflammation and oxidative stress, vasodilation, decreased arterial stiffness, and a reduction in myocardial fibrosiskey factors in the pathophysiology of HFpEF

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Patients who lost less than 20 pounds on GLP-1 medications and were subsequently prescribed phentermine experienced greater weight loss while on phentermine in the year following GLP-1 treatment than patients who lost at least 20 pounds on the GLP-1 medication.

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