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3 months after the desensitization protocol, our patients were still applying exenatide injections without any allergic reactions

Fat tissue produces excess estrogen, which can lead to several types of cancer

Most users experience bloating, gas, or temporary digestive changes during the initial adjustment period

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Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)