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Executive Summary Introduction

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Since 2021, GLP-1s have eroded metformin as the preferred first-line therapy for many patients, despite metformins lower cost and oral administration

With a blend of carefully selected ingredients, this targeted formula helps encourage natural GLP-1 production, without the potentially harmful side effects of synthetic options that have become increasingly popular

The GLP1-RAs vs sodium-glucose cotransporter-2 (SGLT-2) inhibitors cohort included new users of GLP-1 RAs (n=83,464) or SGLT-2 inhibitors (n=78,366), and the GLP1-RAs vs dipeptidyl peptidase-4 (DPP-4) inhibitors cohort included new users of GLP-1 RAs (n=108,322) or DPP-4 inhibitors (n=55,411)
