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Interventions aimed at preserving muscle mass and function such as resistance exercise, sufficient protein intake, optimized nutrition, and appropriate pharmacological agents are essential

As a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor, BRINSUPRI targets neutrophilic inflammation by inhibiting neutrophil serine proteases, addressing a root cause of airway damage, persistent infections, and exacerbations in NCFB

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species

[DOI] [PMC free article] [PubMed] [Google Scholar] 1038.Buse J.B., Rosenstock J., Sesti G., Schmidt W.E., Montanya E., Brett J.H., et al

(2026, March 19)