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Conclusions Patients with T2D starting tirzepatide had greater HbA1c and weight reductions at 12 months post-initiation than those on injectable semaglutide, regardless of previous GLP-1 RA use, consistent with previous clinical trial results.

The misuse of injectable diabetes medications over the past two years has led pharmaceutical companies to develop alternative treatments for weight loss, addressing shortages that affected diabetic pati

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