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The Role of Glp-1 Receptor Agonists in Insulin Resistance with Concomitant Obesity Treatment in Polycystic Ovary Syndrome

GLP-1 drugs can significantly support weight loss and treat symptoms of type 2 diabetes by mimicking a hormone your body naturally uses to regulate your blood sugar and appetite

Plasma DPP-4 activity and TG excursion were reduced, and plasma active GLP-1 was increased, in sitagliptin-treated Dpp4 +/+ mice, but sitagliptin had no effect in Dpp4 / mice (Figure 1, B and C, and Supplemental Figure 3, A and B), consistent with the selectivity of sitagliptin for DPP-4 (22)

There is no information about the maximal duration of this effect

Find out more in this blog post on insulin resistance