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Sormanni P

& Uchigata, Y

For context, most GLP-1 medications require consistent use for weeks or months to start working at full therapeutic capacity

[11] Increased demand for healthier options such as fruits and vegetables (55%), protein shakes, and meal replacements is also seeing growth as they align with the dietary needs of GLP-1 users

Another long acting GLP-1R agonist, dulaglutide (LY2189265, Eli Lilly, structure not shown), is a recombinant fusion protein with two analogs of GLP-1(737) covalently linked by a synthetic 16 amino acid linker to a Fc fragment of human IgG4

The probes were annealed to the complementary toehold sequences that also carry a 10 to 12 bp overhang of A-repeats (Supplemental Table 1)