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Tirzepatide commonly causes nausea, vomiting, diarrhea, and decreased appetite, particularly during initiation and dose escalation

Compared with the TG treatment group, activation of GLP-1R by liraglutide markedly decreased the number of apoptotic cells

a , Tilted view from membrane of the GLP-1R represented as cartoon (cyan) with the peptide 5 agonist in stick representation and carbon, nitrogen and oxygen atoms coloured yellow, blue and red respectively

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The mean duration of exposure to semaglutide or placebo in the study was 34.2 months

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