glp 1 drugs mechanism GLP-1 Receptor Agonists as Treatments for Type 2 Diabetes GLP-1 drugs are expected to

Glucagon-like peptide-1 receptor agonists, namely GLP-1 receptor agonists, are a class of drugs for the treatment of type 2 diabetes.

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The triagonist-induced increase in GSIS was unchanged in the absence of either Gipr or Gcgr

and increased insulin early AUC and C-peptide total and early AUCs

Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)