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Author summary Stem cells lie at the heart of metazoan development, regeneration, and tissue homeostasis, but the molecular basis of their regulation is poorly understood in their natural context within an animal
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The combination therapy of GLP-1 receptor agonists and metformin demonstrates superior safety over monotherapy, while revealing novel adverse events and demographic-specific risk patterns, thereby offering reliable evidence to inform clinical practice.
Screening of one such library comprised of these indoles identifies JWU-A021 to be an especially potent stimulator of glucagon-like peptide-1 (GLP-1) secretion in vitro
