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Description
These include unexplained fatigue, cold intolerance, hair loss, or constipation (suggesting hypothyroidism)

The 22% average reduction by week 12 exceeds what many lipid-lowering medications achieve

Phase 2 research and sponsor-reported Phase 3 data show substantial average weight reductions in selected trial populations receiving structured follow-up

Furthermore, GLP-1 RAs have been shown to improve muscle wasting both by suppressing myostatin expression and promoting the expression of myogenic factors, as well as through anti-inflammatory and anti-apoptotic effects [141,142]

Semaglutide starts at $299/month and tirzepatide at $499/month
Some patients are still clearly able to get these drugs
