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Review Article Other versions: (Verbatim name) ID (Catalog Number) Invalid DOI was provided, please try again ContentsContents Article InfoArticle Info CiteCite MetricsMetrics CommentComment RelatedRelated FigsFigs TabsTabs RefsRefs CitedCited Article title Abstract Keywords Introduction Pharmacogenetics in type 2 diabetes What is glucagon-like peptide-1 (GLP-1) and their role in the glucose metabolism

(2) vigilant monitoring for appetite-related maladaptive responses, including food aversion and dehydration

For example, triple-target agonists like retatrutide are leading multi-target GLP-1 drugs

9 These clinical findings are consistent with preclinical data that berberine activates AMPK and favorably alters lipid metabolism, but the trial did not directly measure GLP-1 or gut microbiota composition

[DOI] [PMC free article] [PubMed] [Google Scholar] 20.An Y.X., Zhang L.C., Fan X.X., Cui K.L., He S.L., Ji P.Y., Tian J.M., Li Z.Y

Group 1: Placebo Group 2 (Low-dose): Phentermine 7.5mg plus Topiramate 46mg once daily Group 3 (High-dose): Phentermine 15mg plus Topiramate 92mg once daily All participants were monitored for a little over 1 year (56 weeks) and were also provided with some lifestyle counselling that included a LEARN manual (I am not actually sure what this means