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Address other health issues

From this point of view, the weight loss effect of SGLT2is, although considered modest and below the clinical significance of 5% overall, has the potential to become the anchor for our efforts to shift the perspective of patients toward healthy behaviors and adherence to treatment

doi: 10.1016/j.bbr.2017.01.004

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The risk compounds significantly for users who also take metformin, as metformin independently reduces B12 absorption

Because of its long half-life of about one week, semaglutide remains in the body for several weeks after the last dose, so effects (both therapeutic and side effects) can persist even after stopping