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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Brown K.F., Rumgay H., Dunlop C., Ryan M., Quartly F., Cox A., Deas A., Elliss-Brookes L., Gavin A., Hounsome L., et al

The coprimary end points were the percentage change in body weight and weight reduction of at least 5%

Furthermore, berberine has been shown to influence weight loss positively by inhibiting the growth of fat cells and promoting the breakdown of existing fat stores
PubMed Central, doi:10.1162/jocn_a_00942

Diabetes was the most common indication (43.9%)

Hypersensitivity myocarditis
