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From rainbow diet pills packed with amphetamines to the rise and fall of fen-phen, the vast majority of weight-loss drugs approved in the United States have been pulled from the marketplace due to unforeseen side effects that turned them into a public health threat

On September 18, 2014, Eli Lilly received FDA approval for TRULICITY

When asked what theyd be willing to give up to afford a GLP-1 prescription, 38% said dining out or takeout, 24% said travel or leisure, and 22% said streaming subscriptions

The theoretical concern about delayed absorption from slowed gastric emptying is unlikely to be clinically significant for hydroxychloroquine due to its very long half-life of 40-50 days

This trend aligns with broader increases in GLP-1 RA utilization across the general population during the same period ( 15 )
