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Moreover, the authors found that the levels of inflammatory markers TNF-, interleukin 6 (IL-6), and matrix metallo-proteinase 9 (MMP-9) were significantly decreased in the CoQ 10 -treated group, while the supplementation did not affect the levels of the anti-inflammatory markers interleukin 4 (IL-4) and tissue growth factor (TGF-), hypothesizing that at the basis of these beneficial effects there are antioxidant and anti-inflammatory activities [89]

La necrosis y apoptosis son los tipos de muerte que mejor han sido estudiados34,4446

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If CPS1 is partially deficient, NCG may stimulate the remaining CPS1.40,41 Initially advocated to NAGS deficiency, its safety, its quick action, and its oral administration incite some authors to propose its use in neonates as soon as they are diagnosed with severe hyperammonemia even before diagnosis confirmation.27,28,40,42,43 The initial dosage is 200 mg/kg (100300 mg/kg) in bolus per nasogastric tube and then 200 mg/kg divided q3h to 6 h
