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A substantial body of evidence indicates the presence of mitochondrial fragmentation in neuronal cells in the brains of HD patients, in which the expression levels of the mitochondrial fission/fusion proteins Drp1, Fis1, and Mfn are significantly altered (Shirendeb et al., 2012)

The discovery of these cells is one of the most important advances in understanding photophobia

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[16] Kuznik B, Khavinson V, Shapovalov K, Linkova N, Lukyanov S, Smolyakov Y, Tereshkov P, Shapovalov Y, Konnov V, Tsybikov N

[DOI] [PubMed] [Google Scholar] 54.Nystedt J., Anderson H., Tikkanen J., Pietila M., Hirvonen T., Takalo R.Lehenkari P