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Description
It plays an essential role in intermediary metabolism

Ideker T
Ongoing phase 3 trials are in progress, and CagriSema is currently under FDA review, with a decision expected in late 2026

The protease reaction was conducted with 50 M of Bz-Nle-Lys-Arg-Arg-AMC and 2.5 L of the tenfold concentrated pellet fraction containing 1.5 g recombinant proteins in 50 mM Tris-HCl, pH 8.0, 1 mM CHAPS, and 20% glycerol at 37 C for 1 h

Bacterial cells containing GST M5-5 were cultivated in the manner described above with the exception that they were grown overnight without addition of an inducer

scRNA-seq reveals ATPIF1 activity in control of T cell antitumor activity
