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Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis

doi: 10.1155/2022/8282387 104 SinghAKTiwariAKSinghPBDwivediUSTrivediSSinghSKet al

From a chemical point of view, this tripeptide has one positively charged amino group and two negatively charged carboxyl groups at a physiological pH
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Compared with controls, adherent SC-islets treated with ZnPTO exhibited a higher proportion of EGFP + GCG + cells, supporting the hypothesis that excessive zinc induces the conversion of SC- cells into SC- cells (Supplementary information, Fig
Conversely, this study had some limitations
