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Finally, we will summarize the currently understood pulmonary consequences of MNPs from the existing in vitro and in vivo studies

One such molecule is the microglial cell surface receptor TREM2 (triggering receptor expressed on myeloid cells 2), which recognizes misfolded proteins like amyloid and activates microglia to clear them

This protein is cleaved by -, , and -secretase enzymes and a complex of proteins containing PS1

Stem Cell Res Ther 10:306 [DOI] [PMC free article] [PubMed] [Google Scholar] 138.Fujisawa K, Hara K, Takami T, Okada S, Matsumoto T, Yamamoto N, Sakaida I (2018) Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells