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Studies have reported that in patients with severe IUA, the recurrence rate can reach up to 62.5% after surgery, primarily due to persistent fibrosis and insufficient angiogenesis during endometrial repair

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Under oxalate stress conditions, both superoxide and the hydroxyl radical are produced in excess amounts.[258] Obviously, the ineffectiveness of Mn-SOD due to Mn deficiency would further enhance the damage due to excess oxalate
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