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Firstly, the reduced insulin-stimulated cell-surface GLUT4 is generally due to an impairment in GLUT4 trafficking rather than a simple reduction in total GLUT4 levels

10.1038/s12276-019-0240-4 11
Significant improvement in the symptom score and flow rate was observed with 1 -AR antagonists alone or combination therapy as compared to placebo or finasteride alone, but there was no significant difference observed for combination therapy over 1 -AR antagonists alone
Cai L, Koropatnick J, Cherian MG: Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro

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To build on our previous findings with ex vivo longitudinal spinal cord slice cultures (Hawker et al., 2024), we next looked at lysolecithin (LPC) to model sustained demyelination in ex vivo brain slice cultures
