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It has therefore been proposed that large doses of NAC like those administered clinically protect against APAP in part by increasing pyruvate oxidation [52,53] an effect that would require the MPC

187 A study also shows that purpurin and its analog, R162, acting as mixed model inhibitors of GDH1, inhibit GDH1 activity, elevate ROS levels and thus attenuate cancer cell proliferation

doi: 10.1021/tx0503449

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Moreover, spinach can block the activity of an enzyme called cholinesterase which is linked to the development of Alzheimer's disease

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