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Archived from the original on 19 April 2024

The First Publication In response to requests from state health officials and medical professionals, the FDA established Approved Drug Products with Therapeutic Equivalence Evaluations via federal rulemaking and the first issue was published on October 31, 1980, hence the name 5 2 9

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Rats were anesthetized by IP injection of a mixture of ketamine (80 mg kg -1 ) and xylazine (10 mg kg -1 )