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The significant reduction of GSH in pbggcs mutants could result in accelerated mitochondrial damage and loss of function, further production of ROS and ultimately, death by apoptosis [38]

Sputum myeloperoxidase in chronic obstructive pulmonary disease

Further studies have implied that HIV-1 icRNA is sensed and signals via the mitochondrial antiviral signaling protein (MAVS) pathway, inducing IFN-I-dependent pro-inflammatory responses in macrophages [41]

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science

Plaques can also form within the connective tissue of neuro-pathways that can cause a host of disorders, conditions, and diseases such as MS, Alzheimers, autism, and autoimmune diseases

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