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doi: 10.3390/foods10061282 85

More work is required to investigate the potential of these scalable organoids in the context of transplantation for bridging therapies but will potentially provide an important treatment modality for non-reversible acute liver failure 79

Toxic solvent residues DMF (dimethylformamide) Known liver toxin Associated with reproductive toxicity Must be removed to extremely low limits in GMP drugs DCM (dichloromethane / methylene chloride) Probable human carcinogen Central nervous system depressant Dangerous even in small amounts if injected TFA (trifluoroacetic acid) Corrosive Can remain in peptides as unmeasured TFA salt Pharmaceutical products often convert TFA salts to safer counterions Without validated HPLC, mass spectrometry, and residual solvent testing, patients may be injected with harmful chemical contaminants

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