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Sci Rep 5:17192

Application of amino acids, tripeptides and chemical agents GSH, Glu-Pro-Ala, L-Glu, and sorbitol were dissolved in growth medium [1/2 MS salts, 1% (w/v) sucrose and 0.05% (w/v) MES], which was then adjusted to pH 5.1

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This process polarizes macrophages towards a pro-inflammatory phenotype, dampens the antigen-presenting capacity of dendritic cells (DCs), and undermines the cytotoxic functions of T and NK cells