glutathione drug class The role of glutathione-S-transferase in anti-cancer resistance Glutathione-responsive nano-vehicles as a promising
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Briefly, 20 mg mouse hippocampal tissue was broken and homogenized in 200 L ATP tissue lysate and centrifuged at 12,000 g for 5 min at 4 C to obtain the supernatant

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The Confidence Tiers We Use in This Review To keep this grounded, each item is labeled by evidence strength and real-world usefulness: Tier 1 (Strong): Consistent benefits across multiple studies and real-world use

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10.1046/j.1365-2710.2003.00493.x

GSH could detoxify heterogeneous substances under the catalysis of Glutathione S-transferases (GST), then secrete them via the multidrug resistance associated proteins (MRPs) efflux pump ( 3 GSH-responsive and -exhausting metal nanomaterials 3.1 Inorganic nanomaterials Inorganic nanomaterials that have intrinsically unique physicochemical properties and can provide satisfactory functionality show enormous potential in biomedical applications, especially in cancer therapy (Wang et al., 2021a)
