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Gene Therapy: Emerging gene-editing technologies such as CRISPR-Cas9 hold promise for correcting FMO3 gene mutations, offering a potentially curative approach for TMAU in the future [18]

thus, it may not be able to detect the lipid-lowering effects in the above subjects

S., Thomas, G

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[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)