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Overall, bromelain appears to exert its biological effects through a multi-target mechanism involving suppression of pro-inflammatory pathways (NF-B, MAPK), activation of antioxidant responses (Nrf2), modulation of immune signaling, and proteolytic regulation of key molecular targets

It is possible, however, to measure levels of endogenous GSH in the brain noninvasively using in vivo magnetic resonance spectroscopy (MRS)

[DOI] [PubMed] [Google Scholar] 100.Ulanovskaya O.A., Zuhl A.M., Cravatt B.F

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Intrafollicular inflammatory cytokines but not steroid hormone concentrations are increased in naturally matured follicles of women with proven endometriosis