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Other cells, such as epithelial cells, can transdifferentiate to CAFs via MMPs, ROS, and tumor-derived transforming growth factor- (TGF-) (76)

Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71

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It is commonly explained as: This simple explanation helps patients better understand the purpose and importance of the treatment

Any perceived benefits typically relate to correction of deficiency symptoms such as fatigue, which may indirectly improve capacity for physical activity