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The typical components include: Vitamin B12 (cobalamin): An essential water-soluble vitamin crucial for red blood cell formation, neurological function, and DNA synthesis

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These conditions can cause B12 levels to rise as a secondary phenomenon

Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone

While not toxic, excessively high doses are usually unnecessary