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Ingraham BC, Barthold D, Fishman P, Coe NB

Figure 2B), supportive of intracellular compensatory mechanisms that mirror the ex vivo (BAL and fresh HAEC) findings

In particular, up-regulation of the transcripts for the rate-limiting enzyme of the TCA cycle, 2-oxoglutarate dehydrogenase (OGDH), and for the TCA-cycle-affiliated proteins, such as subunits of pyruvate dehydrogenase (PDH) and branched chain 2-oxo acids dehydrogenase (BCODH) is observed

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When you wake up, your body is in a fasted state, meaning your stomach is empty

These are crucial cell types involved in the brains response following traumatic brain injury and are needed for specific regions that help develop the central nervous system (CNS)