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In this study, we found that the joint treatment of HT22 cells with very low concentrations of BSO and glutamate, erastin or RSL3 can strongly enhance the induction of ferroptotic cell death, highlighting that PDI is similarly involved in mediating ferroptotic cell death triggered by these chemicals
Additionally, mTORC2 decreases the functionality of the SLC7A11 transporter via phosphorylating SLC7A11 at serine 26 (Gu et al., 2017)
Pirracchio R, et al
It is serious, after all
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