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Agarwal K, Ahn SH, Elkhashab M, et al
Relatively modest changes in MAO-A activity/function can have important neuropsychiatric consequences as demonstrated by the fact that [ 11 C]-harmine-labeled MAO-A is elevated by only 34% throughout the brain of untreated depressed patients compared to controls, yet it appears to be the major contributor to monoamine metabolism in these same patients [13]

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In all these cases, a relationship between an increased resistance to oxidative stress and an extension of life span has been identified [141,142,143,144]

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