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Background: Oxidative stress (OS) is known to play a role in critical illness due to an imbalance in reactive oxygen species (ROS) and reactive nitrogen spe...

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Methods and results To test this hypothesis, we developed a rat model of hyperlipidemia induced by high-fat diet for 16 weeks, during which rats were treated with 1 mg/kg salvianolic acid A (Sal A) for the final 4 weeks
