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While most people tolerate semaglutide well, some do experience side effects, including skin reactions

Metformin Many hypothyroid patients also have insulin resistance or type 2 diabetes and take metformin alongside tirzepatide

It cannot replace it

Basu A, Dube S, Basu R (2017) Men ARE from Mars, women are from Venus: sex differences in insulin action and secretion

High-fat, fried, and very rich foods are the most common triggers for nausea and gastrointestinal discomfort on GLP-1 medications because they slow gastric emptying further on top of the medication's effect

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