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Dies sind kleine Organellen im Zellinneren, die auch als Kraftwerke der Zelle bezeichnet werden, da sie einen Groteil der Energie produzieren

WT1 is necessary for the proliferation and migration of cells of renin lineage following kidney podocyte depletion

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This NAD + deficit directly impairs sirtuin activity (SIRT), compromising their regulation of mitochondrial biogenesis via PGC-1, antioxidant defense through FOXO transcription factors, and metabolic adaptation via HIF-1 modulation [106, 107]