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Mechanistically, Arctigenin downregulated CPT1-mediated FAO, which further inhibited nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome assemblies in macrophages (Qiao et al., 2020)

The other 50-60% is attached to glucuronide to form the inactive conjugate VPAglucuronide (VPA-GLUC), which is then eliminated in bile and urine

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Instrument settings were 10 mW of microwave power, 1 mT of amplitude modulation, 100 kHz of modulation frequency, 150 s of sweep time and 3 scans [16]
