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The up-regulation of MHC-II at the peak of demyelination may be of relevance for the induction of remyelination since MHC-II / mice showed delayed remyelination and regeneration of oligodendrocytes after cuprizone-induced demyelination (Arnett et al., 2012)
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Saxena D, Maitra R, Bormon R, et al

2022;6:e21.00156

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