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In some cases, the lesion may be confined to the mucosa of the lips, and in other cases the lesion may extend past the vermilion border (the edge where the lining on the lips becomes the skin on the face) onto the facial skin

doi: 10.3390/medicines4020037

The biochemical changes, the surface hydrophobicity, and the crosslinking formation caused by oxidation could be reflected by di-tyrosine and disulfide bonds 4 (4, 70)

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4c, Supplemental Table 2)
