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If you have symptoms suggestive of deficiency such as persistent fatigue, neurological symptoms, or unexplained anaemia, consult your GP before self-supplementing

Oral vitamin B12: a costeffective alternative

Patients often experience better coverage and sustained benefits

No human safety data : The complete absence of human clinical trials means the safety profile, side effects, optimal dosing, and pharmacokinetics in humans are entirely unknown Animal-to-human translation is uncertain : Metabolic differences between mice and humans mean that the magnitude of effects (e.g., weight loss, grip strength improvement) may not translate

[DOI] [PubMed] [Google Scholar] 62.Lin C-W, Chen C-Y, Cheng S-J, Hu H-T & Hsueh Y-P Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator

Sun L, Iqbal J, Dolgilevich S, Yuen T, Wu X-B, Moonga BS, et al