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Hearts from heterozygous (GPx1 +/ ) knockout mice were more susceptible to diastolic dysfunction following ischemia/reperfusion (I/R) injury than wildtype hearts [39] and GPx1 / hearts (from male mice) showed both contractile and diastolic dysfunction following I/R, with an increase in oxidative stress as measured by an increase in protein carbonylation [40]

150159, 2014 [44] B

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The role of NCOA4-mediated ferritinophagy in ferroptosis
