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To enable genetic associations to be interpreted in units of weight rather than BMI % , we also defined a corresponding weight phenotype, defined as the change in weight from baseline in kilograms

[89] Due to the peculiar role of senescence in aging and chronic diseases, there has been growing interest in developing vaccines against senescent cells to achieve therapeutic or even preventative effects for these outcomes

In hepatocellular carcinoma cells (HuH7) which originally express CD44s rather than CD44v, silence of CD44 gene impaired the potential of spheroid formation and enhanced sensitivity to sorafenib and 5-fluorouracil (5FU), accompanied by remarkable downregulation of CSC-related genes including CD133 and EpCAM [19]