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Rezafungin (formerly CD101) is a next-generation echinocandin with structural modifications that confer a long half-life (~133 hours), enabling once-weekly intravenous administration

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The cellular and molecular changes triggered by ROS, as previously discussed, disrupt melanocyte homeostasis and contribute to pathological conditions 111

At the cellular level, CKD is remarkable by oxidative stress, abnormal autophagy, and mitochondrial dysfunction accompanied by significant alterations in cell signaling pathways such as HIF, TGF-, and p53 activation [21]

doi: 10.1111/all.13397