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Disruptions in the balance between ROS levels and the bodys antioxidant defenses can lead to the development of numerous diseases

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Distinct variabilities of infection rates, epidemiological transmission, and clinical outcomes during COVID-19 pandemic raises an intriguing question, whether the emergence of SARS-CoV-2 variants of concern (VOCs) with function-specific mutations in ACE2, furin, and TMPRSS2 expression has played any role in disease manifestations and case fatality rates (CFR) 55,75

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IIM, Idiopathic Inflammatory Myopathy