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They are difficult to get rid of, making them similar to fat-soluble toxins
So what do they do

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Jul 26 2021;doi:10.1007/s43032-021-00653-9 Mansour A, Samadi M, Sanginabadi M, et al

How different TME components regulate ferroptosis, including their mechanisms, effects, and targetable nodes is detailed in Table 7

Similar to AD and PD, accumulating evidence suggests that compromised mitophagy lead to the progression of other neurodegenerative diseases, such as HD, ALS, and spinal muscular atrophy (SMA) [136138]
