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We recently reported studies examining a novel glycolipid surfactant-peptide conjugation technology designed to prolong in vivo terminal elimination half-life (T 1/2 ) and demonstrated its tunable impact on pharmacokinetic (PK) parameters for analogs of both parathyroid hormone 19 and GLP-1R/GCGR dual agonists 20

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Chao CY, Battat R, Al Khoury A, Restellini S, Sebastiani G, Bessissow T

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The Science Behind Tirzepatide: Dual-Action Powerhouse Tirzepatide represents a revolutionary advancement in metabolic medicine

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It is worth noting that EQUIP and CONQUER noted mood and memory disturbance, which may be troublesome in older adults, but commonest side effects were dry mouth, paraesthesia, constipation, and insomnia [111, 112]

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Diabetes Care 37 , e11e12 (2014)

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Lack of cardioprotection from subcutaneously and preischemic administered liraglutide in a closed chest porcine ischemia reperfusion model

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