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A decreased HoloTC level along with an increase in the size of the red blood cells (macrocytosis) is a good measure of vitamin B12 deficiency

J Endocrinol (1998) 159(1):11725.10.1677/joe.0.1590117 28 SamuelCS

focused on patients with head and neck cancer, revealing no significant difference in the overall response rate, which represents the percentage of patients achieving complete or partial response, between the glutamine and placebo groups 10 weeks post-chemoradiotherapy completion [123]

A recent in vitro study on human dental pulp cells (hDPCs) indicated that melatonin can promote the odontogenic differentiation of hDPCs, with the simultaneous downregulation of global DNA methylation and MeCP [84]

Therein lies the deeper mystery
